Scale-up refers to the process of taking a small-scale experiment or model and adapting it for larger-scale production or application. The goal of scale-up is to maintain the quality and consistency observed at a smaller scale, whilst achieving mass-production. Processes that are straightforward at small scale may become complex when scaled up due to factors such as resource availability, energy efficiency, distribution of inputs, temperature control, contaminationIn a laboratory setting, contamination refers to the presence of an undesired living organism or oth, system complexity, and cost. Using composting as an example; on a small-scale, the process is easy to manage, relatively quick, and the odour is controlled. Scaling up this process requires additional technical considerations such as advanced ventilation systems for odour control, pest control, mechanical turning and mixing to achieve uniform composting, and temperature and moisture monitoring systems. Scaling manufacture of biotech products often requires additional cost, infrastructure, labour, and presents more technical hurdles.
